TriCos Biotherapeutics – Unique single-chain CD27 agonists for immuno-oncology
  • Activation of CD27 and other TNF receptor superfamily (TNFRSF) members is an attractive approach to stimulate anti-cancer immune response
  • The proprietary trivalent single-chain CD27 ligand (scCD27L) module allows the construction of hexavalent systemic – and bispecific tumor-targeted molecules
  • The unique properties of the trivalent scCD27L module enables the development of attractive drug candidates superior to other approaches
  • The bispecific SAB construction principle is a platform approach and ready to be applied to different TNFSF ligands (4-1BBL, GITRL, CD40L, LIGHT) and/or tumor targets